STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eng-1Glyco_hydro_85 domain-containing protein. (433 aa)    
Predicted Functional Partners:
msp-33
Major sperm protein 33; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
      
 0.850
far-1
Fatty-acid and retinol-binding protein 1; Probably binds lipids; Belongs to the fatty-acid and retinol-binding protein (FARBP) family.
      
 0.805
vap-2
Venom-Allergen-like Protein; Belongs to the CRISP family.
      
 0.717
vap-1
Venom-Allergen-like Protein; Belongs to the CRISP family.
      
 0.697
col-176
Col_cuticle_N domain-containing protein.
      
 0.693
cyp-31A2
CYtochrome P450 family; Belongs to the cytochrome P450 family.
   
  
 0.669
crt-1
Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle (By similarity). This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis. Protects dopaminergic neurons against oxidative stress-induced neurodegen [...]
      
 0.669
msp-10
Major sperm protein 10/36/56/76.
      
 0.660
srp-8
SERPIN domain-containing protein; Belongs to the serpin family.
      
 0.620
C34E7.4
Uncharacterized protein.
      
 0.587
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.