STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpo-10Uncharacterized protein. (646 aa)    
Predicted Functional Partners:
C27F2.10
PCI domain-containing protein 2 homolog; Belongs to the CSN12 family.
   
 
 0.962
dss-1
Probable 26S proteasome complex subunit dss-1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Has an essential role in oogenesis and larval growth. Required for intestinal function and default lifespan.
    
 
 0.875
C27F2.7
Uncharacterized F-box protein C27F2.7.
   
 
 0.854
magi-1
MAGI (Membrane Associated Guanylate kinase Inverted) homolog.
    
 
 0.555
ttyh-1
Protein tweety homolog 1; Probable chloride channel.
   
  
 0.552
rsy-1
Regulator of SYnapse formation.
   
 
 0.533
snpc-4
snRNA-activating protein complex subunit 4 homolog; Binds to the promoter regions of RNA polymerase II and III small-nuclear RNA genes, type 3 RNA polymerase III non-coding RNA genes, small nucleolar RNAs and transfer RNA genes. Required for expression of mature 21U-RNAs.
   
    0.519
C34D10.2
Uncharacterized protein.
      
 0.477
ola-1
Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
   
  
 0.434
unc-76
Uncharacterized protein.
   
  
 0.410
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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