STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rabn-5FYVE-type domain-containing protein. (414 aa)    
Predicted Functional Partners:
rab-5
RAB family.
   
 
 0.957
rme-6
Receptor-mediated endocytosis protein 6; Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in endocytosis. Acts by regulating the activation of rab-5 by exchanging bound GDP for free GTP at clathrin coated pits.
   
 
 0.954
rabx-5
RAB eXchange factor.
   
 
 0.934
apt-9
AdaPTin or adaptin-related protein.
    
 
 0.918
Y39A1A.24
Uncharacterized protein.
   
 
 0.850
rabs-5
FYVE-type domain-containing protein.
   
  
 0.799
F22G12.4
Uncharacterized protein.
   
 
 0.797
F13E9.1
PX domain-containing protein.
   
  
 0.771
rskd-1
PX domain-containing protein.
   
  
 0.767
F22D6.2
Uncharacterized protein.
   
 
 0.743
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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