STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F01G10.10Uncharacterized protein. (562 aa)    
Predicted Functional Partners:
K06G5.1
VWFA domain-containing protein.
   
  
 0.760
uggt-2
UDP-Glucose Glycoprotein glucosylTransferase.
      
 0.741
lbp-2
Fatty acid-binding protein homolog 2; May play a role in sequestering potentially toxic fatty acids and their peroxidation products, or it may be involved in the maintenance of the impermeable lipid layer of the eggshell.
      
 0.698
malt-1
MALT1 paracaspase homolog.
      
 0.660
lbp-3
Fatty acid-binding protein homolog 3; May play a role in sequestering potentially toxic fatty acids and their peroxidation products, or it may be involved in the maintenance of the impermeable lipid layer of the eggshell. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      
 0.620
tth-1
Thymosin beta; Plays an important role in the organization of the cytoskeleton by regulating actin polymerization in two ways. Firstly, by binding to and sequestering actin monomers (G actin) inhibits actin polymerization. Secondly, by binding directly filamentous actin (F actin) promotes actin polymerization. Regulates the formation of cortical actin in oocytes conferring them enough rigidity to sustain the contractions during ovulation.
      
 0.581
rpl-27
60S ribosomal protein L27; Component of the large ribosomal subunit.
   
  
 0.467
C05C9.1
Uncharacterized protein.
   
  
0.448
C06G1.1
BPI2 domain-containing protein.
   
  
0.445
acdh-6
Probable acyl-CoA dehydrogenase 6; Belongs to the acyl-CoA dehydrogenase family.
   
    0.444
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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