STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ard-1Alcohol/Ribitol Dehydrogenase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa)    
Predicted Functional Partners:
ech-6
Probable enoyl-CoA hydratase, mitochondrial.
   
 
 0.985
ech-7
Enoyl-CoA Hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 
 0.984
acaa-2
ACetyl-CoA Acyltransferase 2 homolog; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.976
B0303.3
Uncharacterized protein B0303.3; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.965
F46F11.10
SAM-dependent MTase TRM10-type domain-containing protein.
    
 
 0.962
ech-1.2
Enoyl-CoA Hydratase.
   
 
 0.952
coa-6
Cytochrome Oxidase Assembly subunits.
   
 
 0.952
ech-1.1
Enoyl-CoA Hydratase.
   
 
 0.951
F23C8.5
ETF domain-containing protein.
   
  
 0.808
dhc-1
Dynein heavy chain, cytoplasmic; Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules (By similarity). Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). May play a role in nuclear migration in hypodermal precursor cells. May be involved in the transport of synaptic vesicle components towards the axon of the DA motor neuron. This function may involve the regulation of dynein by pct-1 and/or cdk-5. Involved in the formation of synapses in the dorsal regi [...]
 
      0.719
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.