STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
skih-2SKI (Yeast SuperKIller) Helicase homolog. (1266 aa)    
Predicted Functional Partners:
ttc-37
TeTratriCopeptide repeat domain protein related.
   
 0.999
F02E9.10
WD_REPEATS_REGION domain-containing protein.
    
 0.998
rps-30
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
   0.988
pelo-1
Protein pelota homolog; Required for normal chromosome segregation during cell division and genomic stability. May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity.
   
 
 0.976
xrn-1
5'-3' exoribonuclease 1.
   
 
 0.962
exos-7
RNase_PH domain-containing protein.
   
 0.937
exos-9
EXOSome (Multiexonuclease complex) component.
   
 0.937
exos-1
ECR1_N domain-containing protein.
   
 0.937
crn-3
HRDC domain-containing protein.
   
 
 0.929
exos-3
KH_dom_type_1 domain-containing protein.
   
 0.927
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.