STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wht-4ABC transporter domain-containing protein. (636 aa)    
Predicted Functional Partners:
ZK354.7
Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
   
  
 0.888
oac-9
NRF domain-containing protein.
   
  
 0.783
K05F1.9
Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
   
  
 0.742
flp-19
FMRFamide-like neuropeptides 19; FMRFamides and FMRFamide-like peptides are neuropeptides. WANQVRF-amide inhibits the activity of dissected pharyngeal myogenic muscle system; Belongs to the FARP (FMRFamide related peptide) family.
      
 0.660
gcy-9
Receptor-type guanylate cyclase gcy-9; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Involved in the sensing of CO2 levels and acidity by the BAG neurons. May act as a direct receptor for CO2 and H+.
      
 0.660
wht-8
ABC transporter domain-containing protein.
  
  
0.635
C34D4.2
Serine/threonine-protein phosphatase.
   
   0.633
acs-18
AMP-binding domain-containing protein.
   
 
 0.633
F44G3.7
Uncharacterized protein; Belongs to the serpin family.
   
   0.632
F58G1.3
Serine/threonine-protein phosphatase.
   
   0.632
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.