node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
T22D1.5 | clec-88 | T22D1.5.1 | K10B2.3b.2 | Uncharacterized protein. | C-type lectin domain-containing protein 88. | 0.999 |
T22D1.5 | egg-1 | T22D1.5.1 | B0244.8.1 | Uncharacterized protein. | LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial. Redundantly with egg-2, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required together with egg-2 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane. Appears to recruit or maint [...] | 0.922 |
T22D1.5 | inx-14 | T22D1.5.1 | F07A5.1b.1 | Uncharacterized protein. | Innexin-14; Structural component of the gap junctions. | 0.925 |
T22D1.5 | inx-22 | T22D1.5.1 | Y47G6A.2.2 | Uncharacterized protein. | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. | 0.556 |
T22D1.5 | puf-3 | T22D1.5.1 | Y45F10A.2.1 | Uncharacterized protein. | PUM-HD domain-containing protein. | 0.999 |
ceh-18 | fog-2 | ZC64.3a.1 | Y113G7B.5b.1 | Homeobox protein ceh-18; Directs gonadal sheath cell differentiation and function. Also directs gonad migration and plays a role in specifying the differentiated phenotypes of epidermal cells during postembryonic development. Plays a role in oogenesis, regulating a sheath cell signal that causes oocytes to maintain diakinesis arrest during meiosis. Negatively regulates oocyte maturation, ovulation and MAPK activation in oocytes when sperm are not available for fertilization. May be recruited by akir-1 to the promoter regions of antimicrobial peptide genes to control gene expression in [...] | F-box domain-containing protein. | 0.531 |
ceh-18 | inx-14 | ZC64.3a.1 | F07A5.1b.1 | Homeobox protein ceh-18; Directs gonadal sheath cell differentiation and function. Also directs gonad migration and plays a role in specifying the differentiated phenotypes of epidermal cells during postembryonic development. Plays a role in oogenesis, regulating a sheath cell signal that causes oocytes to maintain diakinesis arrest during meiosis. Negatively regulates oocyte maturation, ovulation and MAPK activation in oocytes when sperm are not available for fertilization. May be recruited by akir-1 to the promoter regions of antimicrobial peptide genes to control gene expression in [...] | Innexin-14; Structural component of the gap junctions. | 0.699 |
ceh-18 | inx-22 | ZC64.3a.1 | Y47G6A.2.2 | Homeobox protein ceh-18; Directs gonadal sheath cell differentiation and function. Also directs gonad migration and plays a role in specifying the differentiated phenotypes of epidermal cells during postembryonic development. Plays a role in oogenesis, regulating a sheath cell signal that causes oocytes to maintain diakinesis arrest during meiosis. Negatively regulates oocyte maturation, ovulation and MAPK activation in oocytes when sperm are not available for fertilization. May be recruited by akir-1 to the promoter regions of antimicrobial peptide genes to control gene expression in [...] | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. | 0.690 |
clec-88 | T22D1.5 | K10B2.3b.2 | T22D1.5.1 | C-type lectin domain-containing protein 88. | Uncharacterized protein. | 0.999 |
clec-88 | egg-1 | K10B2.3b.2 | B0244.8.1 | C-type lectin domain-containing protein 88. | LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial. Redundantly with egg-2, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required together with egg-2 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane. Appears to recruit or maint [...] | 0.585 |
clec-88 | inx-14 | K10B2.3b.2 | F07A5.1b.1 | C-type lectin domain-containing protein 88. | Innexin-14; Structural component of the gap junctions. | 0.846 |
clec-88 | puf-3 | K10B2.3b.2 | Y45F10A.2.1 | C-type lectin domain-containing protein 88. | PUM-HD domain-containing protein. | 0.999 |
egg-1 | T22D1.5 | B0244.8.1 | T22D1.5.1 | LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial. Redundantly with egg-2, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required together with egg-2 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane. Appears to recruit or maint [...] | Uncharacterized protein. | 0.922 |
egg-1 | clec-88 | B0244.8.1 | K10B2.3b.2 | LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial. Redundantly with egg-2, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required together with egg-2 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane. Appears to recruit or maint [...] | C-type lectin domain-containing protein 88. | 0.585 |
egg-1 | inx-14 | B0244.8.1 | F07A5.1b.1 | LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial. Redundantly with egg-2, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required together with egg-2 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane. Appears to recruit or maint [...] | Innexin-14; Structural component of the gap junctions. | 0.695 |
egg-1 | inx-22 | B0244.8.1 | Y47G6A.2.2 | LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial. Redundantly with egg-2, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required together with egg-2 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane. Appears to recruit or maint [...] | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. | 0.426 |
egg-1 | puf-3 | B0244.8.1 | Y45F10A.2.1 | LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial. Redundantly with egg-2, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required together with egg-2 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane. Appears to recruit or maint [...] | PUM-HD domain-containing protein. | 0.999 |
fog-2 | ceh-18 | Y113G7B.5b.1 | ZC64.3a.1 | F-box domain-containing protein. | Homeobox protein ceh-18; Directs gonadal sheath cell differentiation and function. Also directs gonad migration and plays a role in specifying the differentiated phenotypes of epidermal cells during postembryonic development. Plays a role in oogenesis, regulating a sheath cell signal that causes oocytes to maintain diakinesis arrest during meiosis. Negatively regulates oocyte maturation, ovulation and MAPK activation in oocytes when sperm are not available for fertilization. May be recruited by akir-1 to the promoter regions of antimicrobial peptide genes to control gene expression in [...] | 0.531 |
fog-2 | inx-14 | Y113G7B.5b.1 | F07A5.1b.1 | F-box domain-containing protein. | Innexin-14; Structural component of the gap junctions. | 0.816 |
fog-2 | inx-22 | Y113G7B.5b.1 | Y47G6A.2.2 | F-box domain-containing protein. | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. | 0.570 |