STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srh-234Serpentine Receptor, class H. (334 aa)    
Predicted Functional Partners:
srh-34
Serpentine Receptor, class H.
   
  
 0.855
mef-2
MADS-box domain-containing protein.
      
 0.759
odr-10
Serpentine receptor class r-10; An odorant receptor which affects chemotaxis to the volatile odorant diacetyl. Specifies AWA neuronal cell fate via the odr-7 pathway; Belongs to the nematode receptor-like protein str family.
      
 0.758
str-148
Seven TM Receptor.
      
 0.697
sre-1
Serpentine receptor class epsilon-1.
   
  
 0.667
kin-29
Serine/threonine-protein kinase kin-29; Regulates chemoreceptor expression by phosphorylating the hda-4 class II histone deacetylase (HDAC) and inhibiting the gene repression functions of hda-4 and the mef-2 transcription factor, enabling the correct sensing and transduction of food signals. Role in determining body size, the dauer decision and serotonin-mediated egg laying. May modulate the Sma/Mab pathway and regulates development in the later larval stages.
      
 0.660
srd-1
Serpentine receptor class delta-1.
   
  
 0.475
ncx-6
Putative sodium/calcium exchanger 6.
      
 0.463
npr-1
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.463
ins-1
IlGF domain-containing protein.
      
 0.459
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.