STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F07H5.10RAI1 domain-containing protein. (334 aa)    
Predicted Functional Partners:
xrn-2
5'-3' exoribonuclease 2 homolog; Possesses 5'->3' exoribonuclease activity. Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA. Degradation role is enhanced when in complex with paxt-1. Partially redundant to xrn-1 in miRNA guide strand degradation. Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA. Positively regulates molting of the pharyngeal cuticle.
   
 
 0.812
exos-7
RNase_PH domain-containing protein.
   
   0.725
cids-1
CID domain-containing protein 1.
   
 
 0.576
rsa-1
Serine/threonine-protein phosphatase 2A regulatory subunit rsa-1; Regulatory subunit of phosphatase let-92 which recruits let- 92/paa-1 complex to the centrosomes, thereby regulating microtubule outgrowth from centrosomes and mitotic spindle assembly ensuring the stability of kinetochore microtubules.
   
    0.544
skr-17
SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family.
   
    0.539
gna-2
Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily.
   
    0.537
cids-2
CID domain-containing protein.
   
 
 0.536
C37C3.9
BTB domain-containing protein.
   
    0.529
dyf-19
Uncharacterized protein.
    
 
 0.522
hrde-2
Protein hrde-2; Plays a role in germline RNA interference (RNAi), and in particular is required for piwi-interacting RNA (piRNA) gene silencing. Facilitates the binding of the argonaut protein hrde-1 to small interfering RNAs (siRNAs) targets that are required for transgenerational epigenetic inheritance and germline immortality.
   
    0.515
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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