STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdh-5CaDHerin family. (1449 aa)    
Predicted Functional Partners:
lhfp-4
Lipoma Hmgic (HMGIC) Fusion Partner-like homolog.
   
 
 0.935
hmr-1
Cadherin-related hmr-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Required for adherens junction assembly and connecting adherens junctions to the cytoskeleton. Isoform b is involved in axonal guidance in a subset of motor neurons.
   
 
0.753
cdh-1
CaDHerin family.
   
 
0.744
cdh-8
CaDHerin family.
   
 
0.734
casy-1
CAlSYntenin/Alcadein homolog.
   
  
 0.724
fmil-1
GPS domain-containing protein.
   
  
 0.709
Y52B11A.11
Uncharacterized protein.
   
 
 0.707
act-5
ACTin.
   
 
 0.705
R02E12.4
Uncharacterized protein.
   
  
 0.680
exl-1
Chloride intracellular channel exl-1; Probable chloride channel; Belongs to the chloride channel CLIC family.
    
 
 0.672
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.