node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C27A7.6 | erd-2 | C27A7.6c.1 | F09B9.3.1 | Uncharacterized protein. | ER lumen protein-retaining receptor erd-2.1; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity); Belongs to the ERD2 family. | 0.910 |
C27A7.6 | marc-4 | C27A7.6c.1 | C53D5.2.1 | Uncharacterized protein. | RING-CH-type domain-containing protein. | 0.971 |
F47G9.1 | copb-1 | F47G9.1.1 | Y25C1A.5.1 | GOLD domain-containing protein. | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. | 0.787 |
F47G9.1 | erd-2 | F47G9.1.1 | F09B9.3.1 | GOLD domain-containing protein. | ER lumen protein-retaining receptor erd-2.1; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity); Belongs to the ERD2 family. | 0.717 |
F47G9.1 | nsf-1 | F47G9.1.1 | H15N14.2a.1 | GOLD domain-containing protein. | Vesicle-fusing ATPase; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity); Belongs to the AAA ATPase family. | 0.499 |
F47G9.1 | sec-12 | F47G9.1.1 | K02B12.3.2 | GOLD domain-containing protein. | WD_REPEATS_REGION domain-containing protein. | 0.461 |
F47G9.1 | uso-1 | F47G9.1.1 | K09B11.9a.1 | GOLD domain-containing protein. | USO1 (Yeast transport protein) homolog. | 0.517 |
F47G9.1 | ykt-6 | F47G9.1.1 | B0361.10.1 | GOLD domain-containing protein. | YKT6 (Yeast v-SNARE) homolog; Belongs to the synaptobrevin family. | 0.530 |
acl-8 | erd-2 | T05H4.1.1 | F09B9.3.1 | PlsC domain-containing protein. | ER lumen protein-retaining receptor erd-2.1; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity); Belongs to the ERD2 family. | 0.710 |
copb-1 | F47G9.1 | Y25C1A.5.1 | F47G9.1.1 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. | GOLD domain-containing protein. | 0.787 |
copb-1 | erd-2 | Y25C1A.5.1 | F09B9.3.1 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. | ER lumen protein-retaining receptor erd-2.1; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity); Belongs to the ERD2 family. | 0.733 |
copb-1 | nsf-1 | Y25C1A.5.1 | H15N14.2a.1 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. | Vesicle-fusing ATPase; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity); Belongs to the AAA ATPase family. | 0.568 |
copb-1 | uso-1 | Y25C1A.5.1 | K09B11.9a.1 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. | USO1 (Yeast transport protein) homolog. | 0.816 |
copb-1 | ykt-6 | Y25C1A.5.1 | B0361.10.1 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. | YKT6 (Yeast v-SNARE) homolog; Belongs to the synaptobrevin family. | 0.550 |
dnj-7 | erd-2 | C55B6.2.1 | F09B9.3.1 | DNaJ domain (Prokaryotic heat shock protein). | ER lumen protein-retaining receptor erd-2.1; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity); Belongs to the ERD2 family. | 0.745 |
erd-2 | C27A7.6 | F09B9.3.1 | C27A7.6c.1 | ER lumen protein-retaining receptor erd-2.1; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity); Belongs to the ERD2 family. | Uncharacterized protein. | 0.910 |
erd-2 | F47G9.1 | F09B9.3.1 | F47G9.1.1 | ER lumen protein-retaining receptor erd-2.1; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity); Belongs to the ERD2 family. | GOLD domain-containing protein. | 0.717 |
erd-2 | acl-8 | F09B9.3.1 | T05H4.1.1 | ER lumen protein-retaining receptor erd-2.1; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity); Belongs to the ERD2 family. | PlsC domain-containing protein. | 0.710 |
erd-2 | copb-1 | F09B9.3.1 | Y25C1A.5.1 | ER lumen protein-retaining receptor erd-2.1; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity); Belongs to the ERD2 family. | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. | 0.733 |
erd-2 | dnj-7 | F09B9.3.1 | C55B6.2.1 | ER lumen protein-retaining receptor erd-2.1; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity); Belongs to the ERD2 family. | DNaJ domain (Prokaryotic heat shock protein). | 0.745 |