STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ggr-3GABA/Glycine Receptor family (See gbr); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (445 aa)    
Predicted Functional Partners:
madf-1
MADF domain-containing protein.
      
 0.668
lgc-25
Neur_chan_LBD domain-containing protein.
  
   
 0.650
lgc-23
Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
   
 0.634
lgc-12
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
  
 0.622
col-14
Cuticle collagen 14; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment.
      
 0.551
nfya-1
Nuclear transcription Factor Y, A (Alpha) subunit.
      
 0.537
lgc-30
Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
    0.533
acr-5
Acetylcholine receptor subunit alpha-type acr-5; Possible acetylcholine receptor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
  
    0.532
lgc-8
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
     0.519
lgc-7
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
     0.516
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.