STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F09C12.2Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (418 aa)    
Predicted Functional Partners:
Y47G6A.5
Tyrosine-protein kinase.
  
 
 
 0.816
F26A10.2
Uncharacterized protein.
    
 
 0.731
F45E10.2
MFS domain-containing protein.
   
 
 0.702
mak-2
MAP kinase-activated protein kinase mak-2; Serine/threonine-protein kinase which is involved in maintaining synapse and axon morphology as well as touch neuron axon regeneration after injury by regulating cebp-1 mRNA stability downstream of the dlk-1, mkk-4 and pmk-3 signaling cascade. May play a role in body wall muscle contraction. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord.
  
 
0.698
C18H7.11
Uncharacterized protein.
      
 0.697
C18H9.1
Uncharacterized protein.
      
 0.697
K03H1.5
Uncharacterized protein K03H1.5.
      
 0.696
M28.8
Uncharacterized protein.
      
 0.696
ensh-1
Fibrinogen C-terminal domain-containing protein.
      
 0.695
swt-6
Sugar transporter SWEET; Mediates sugar transport across membranes. Belongs to the SWEET sugar transporter family.
      
 0.694
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.