node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cosa-1 | him-14 | Y71H2AM.7.1 | ZK1127.11.1 | CrossOver Site Associated. | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | 0.887 |
cosa-1 | mlh-1 | Y71H2AM.7.1 | T28A8.7.1 | CrossOver Site Associated. | DNA_mis_repair domain-containing protein. | 0.486 |
cosa-1 | msh-5 | Y71H2AM.7.1 | F09E8.3a.1 | CrossOver Site Associated. | MutS protein homolog 5; Crucial component in meiotic recombination, functioning at some point after the initiation step of recombination. Plays a role in promoting the crossover outcome of meiotic recombination events. Required for formation of normal meiotic crossover, and crossover and chiasmata generated by artificially made DNA breaks. | 0.944 |
cosa-1 | mus-81 | Y71H2AM.7.1 | C43E11.2a.1 | CrossOver Site Associated. | ERCC4 domain-containing protein. | 0.707 |
cosa-1 | rad-51 | Y71H2AM.7.1 | Y43C5A.6a.1 | CrossOver Site Associated. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. | 0.862 |
cosa-1 | rmh-1 | Y71H2AM.7.1 | M01E11.3.1 | CrossOver Site Associated. | DUF1767 domain-containing protein. | 0.856 |
cosa-1 | spo-11 | Y71H2AM.7.1 | T05E11.4a.1 | CrossOver Site Associated. | Meiotic recombination protein spo-11; Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. | 0.923 |
cosa-1 | syp-2 | Y71H2AM.7.1 | C24G6.1.1 | CrossOver Site Associated. | Uncharacterized protein. | 0.885 |
cosa-1 | zhp-3 | Y71H2AM.7.1 | K02B12.8b.1 | CrossOver Site Associated. | RING-type domain-containing protein. | 0.928 |
him-14 | cosa-1 | ZK1127.11.1 | Y71H2AM.7.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | CrossOver Site Associated. | 0.887 |
him-14 | mlh-1 | ZK1127.11.1 | T28A8.7.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | DNA_mis_repair domain-containing protein. | 0.991 |
him-14 | msh-5 | ZK1127.11.1 | F09E8.3a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | MutS protein homolog 5; Crucial component in meiotic recombination, functioning at some point after the initiation step of recombination. Plays a role in promoting the crossover outcome of meiotic recombination events. Required for formation of normal meiotic crossover, and crossover and chiasmata generated by artificially made DNA breaks. | 0.999 |
him-14 | mus-81 | ZK1127.11.1 | C43E11.2a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | ERCC4 domain-containing protein. | 0.979 |
him-14 | pms-2 | ZK1127.11.1 | H12C20.2a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | PMS (Post Meiotic Segregation) family. | 0.942 |
him-14 | rad-51 | ZK1127.11.1 | Y43C5A.6a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. | 0.935 |
him-14 | rmh-1 | ZK1127.11.1 | M01E11.3.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | DUF1767 domain-containing protein. | 0.847 |
him-14 | spo-11 | ZK1127.11.1 | T05E11.4a.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | Meiotic recombination protein spo-11; Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. | 0.991 |
him-14 | syp-2 | ZK1127.11.1 | C24G6.1.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | Uncharacterized protein. | 0.844 |
him-14 | zhp-3 | ZK1127.11.1 | K02B12.8b.1 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. | RING-type domain-containing protein. | 0.922 |
mlh-1 | cosa-1 | T28A8.7.1 | Y71H2AM.7.1 | DNA_mis_repair domain-containing protein. | CrossOver Site Associated. | 0.486 |