STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
str-97Seven TM Receptor. (363 aa)    
Predicted Functional Partners:
flr-2
CTCK domain-containing protein.
      
 0.808
gur-5
GUstatory Receptor family.
    
 
 0.776
gur-4
GUstatory Receptor family.
    
 
 0.761
gur-3
Gustatory receptor family protein 3; Chemoreceptor involved in light-induced avoidance behavior. Probably acts as a molecular sensor in I2 pharyngeal neurons, required for the inhibition of feeding in response to light and hydrogen peroxide. Involved in circadian rhythms, probably by acting as a light sensor. In contrast to lite-1, does not act as a photoreceptor.
    
 
 0.706
glr-7
GLutamate Receptor family (AMPA); Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
   
  
 0.703
glr-8
Lig_chan-Glu_bd domain-containing protein.
      
 0.669
spp-12
Saposin B-type domain-containing protein.
      
 0.669
ceh-34
Homeobox protein ceh-34; Acts as a transcription regulator. Binds to the cis-regulatory element of proapoptotic factor egl-1 gene and together with eya-1 activates egl-1 expression to promote motor neuron M4 sister cell apoptosis. Also promotes apoptosis of I1 pharyngeal neuron sister cell. Together with eya- 1, required to specify the coelomocyte fate in embryonic and postembryonic precursors. Belongs to the SIX/Sine oculis homeobox family.
    
 
 0.592
F13H10.6
Uncharacterized protein.
      
 0.535
C54E4.4
Uncharacterized protein.
      
 0.532
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.