STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sod-2Superoxide dismutase [Mn] 1, mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. (221 aa)    
Predicted Functional Partners:
sod-1
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity). Required for normal brood size. May be involved in regulating mpk-1 phosphorylation downstream of phosphatase ptp-2 during oocyte maturation.
   
 0.976
sod-4
Extracellular superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.
   
 0.963
sod-5
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.963
mrpl-17
Mitochondrial Ribosomal Protein, Large.
   
 0.905
sod-3
Superoxide dismutase [Mn] 2, mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
  
  
 
0.900
mrps-18C
Putative 39S ribosomal protein L3, mitochondrial.
  
 
 0.897
mrpl-13
Mitochondrial Ribosomal Protein, Large.
  
 
 0.896
gpx-1
Glutathione peroxidase 1; May constitute a glutathione peroxidase-like protective system against oxidative stresses.
   
 0.895
rps-11
Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family.
  
 
 0.893
rpl-23
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.891
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.