node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C24A1.3 | sel-2 | C24A1.3a.1 | F10F2.1.1 | Uncharacterized protein. | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. | 0.764 |
C24A1.3 | sel-5 | C24A1.3a.1 | F35G12.3a.2 | Uncharacterized protein. | Serine/threonine-protein kinase sel-5; Serine/threonine-protein kinase which may play a role in lin- 12-mediated cell-fate decisions. | 0.723 |
ctps-1 | ddx-27 | W06H3.3.1 | Y71G12B.8.1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | DEAD boX helicase homolog; Belongs to the DEAD box helicase family. | 0.470 |
ctps-1 | sel-2 | W06H3.3.1 | F10F2.1.1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. | 0.547 |
ddx-27 | ctps-1 | Y71G12B.8.1 | W06H3.3.1 | DEAD boX helicase homolog; Belongs to the DEAD box helicase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.470 |
ddx-27 | npr-23 | Y71G12B.8.1 | Y34D9A.2.1 | DEAD boX helicase homolog; Belongs to the DEAD box helicase family. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.781 |
ddx-27 | sel-2 | Y71G12B.8.1 | F10F2.1.1 | DEAD boX helicase homolog; Belongs to the DEAD box helicase family. | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. | 0.750 |
lin-12 | sel-1 | R107.8.1 | F45D3.5.2 | Protein lin-12; Involved in several cell fate decisions that require cell- cell interactions. It is possible that lin-12 encodes a membrane-bound receptor for a signal that enables expression of the ventral uterine precursor cell fate. Activity in cell fate decisions and tumorigenesis is negatively regulated by sel-10. Functions in uterine cells to promote basement membrane mobility during tissue remodeling. | Suppressor/Enhancer of Lin-12. | 0.813 |
lin-12 | sel-2 | R107.8.1 | F10F2.1.1 | Protein lin-12; Involved in several cell fate decisions that require cell- cell interactions. It is possible that lin-12 encodes a membrane-bound receptor for a signal that enables expression of the ventral uterine precursor cell fate. Activity in cell fate decisions and tumorigenesis is negatively regulated by sel-10. Functions in uterine cells to promote basement membrane mobility during tissue remodeling. | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. | 0.617 |
mab-21 | npr-23 | F35G12.6.1 | Y34D9A.2.1 | Protein male abnormal 21; Acts in a cell autonomous fashion to specify the properties of the sensory ray and non-autonomously in the choice of hypodermal versus neuroblast cell fate. Belongs to the mab-21 family. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.660 |
mab-21 | sel-2 | F35G12.6.1 | F10F2.1.1 | Protein male abnormal 21; Acts in a cell autonomous fashion to specify the properties of the sensory ray and non-autonomously in the choice of hypodermal versus neuroblast cell fate. Belongs to the mab-21 family. | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. | 0.734 |
moc-1 | sel-2 | T06H11.4.1 | F10F2.1.1 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. | 0.540 |
npr-23 | ddx-27 | Y34D9A.2.1 | Y71G12B.8.1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | DEAD boX helicase homolog; Belongs to the DEAD box helicase family. | 0.781 |
npr-23 | mab-21 | Y34D9A.2.1 | F35G12.6.1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | Protein male abnormal 21; Acts in a cell autonomous fashion to specify the properties of the sensory ray and non-autonomously in the choice of hypodermal versus neuroblast cell fate. Belongs to the mab-21 family. | 0.660 |
npr-23 | sel-2 | Y34D9A.2.1 | F10F2.1.1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. | 0.577 |
sel-1 | lin-12 | F45D3.5.2 | R107.8.1 | Suppressor/Enhancer of Lin-12. | Protein lin-12; Involved in several cell fate decisions that require cell- cell interactions. It is possible that lin-12 encodes a membrane-bound receptor for a signal that enables expression of the ventral uterine precursor cell fate. Activity in cell fate decisions and tumorigenesis is negatively regulated by sel-10. Functions in uterine cells to promote basement membrane mobility during tissue remodeling. | 0.813 |
sel-1 | sel-2 | F45D3.5.2 | F10F2.1.1 | Suppressor/Enhancer of Lin-12. | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. | 0.693 |
sel-2 | C24A1.3 | F10F2.1.1 | C24A1.3a.1 | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. | Uncharacterized protein. | 0.764 |
sel-2 | ctps-1 | F10F2.1.1 | W06H3.3.1 | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.547 |
sel-2 | ddx-27 | F10F2.1.1 | Y71G12B.8.1 | Putative neurobeachin homolog; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins (By similarity). Regulates endosomal traffic in polarized epithelial cells such as the vulval precursor cells and intestinal cells. Thought to act as a negative regulator of lin-12 activity in vulval precursor cells. May have a role in the internalization process from basolateral surface of polarized epithelial cells. | DEAD boX helicase homolog; Belongs to the DEAD box helicase family. | 0.750 |