STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pqn-29Prion-like-(Q/N-rich)-domain-bearing protein. (549 aa)    
Predicted Functional Partners:
pqn-63
Prion-like-(Q/N-rich)-domain-bearing protein.
   
 
 0.821
moa-1
Modifier Of Apl-1 activity.
      
 0.817
abu-14
Activated in Blocked Unfolded protein response.
   
 
 0.723
ebax-1
SWIM-type domain-containing protein.
      
 0.698
pqn-74
Chitin-binding type-2 domain-containing protein.
   
  
 0.697
abu-11
Activated in Blocked Unfolded protein response.
   
 
 0.596
ham-1
Stork_head domain-containing protein.
      
 0.533
mlc-3
Myosin, essential light chain.
   
 
 0.505
unc-89
Muscle M-line assembly protein unc-89; Structural component of the muscle M line which is involved in assembly and organization of sarcomere myofilaments. The large isoform a, isoform b, isoform d and isoform f play an essential role in maintaining the organization of sarcomeres but not myofilament alignment during body wall muscle development whereas the small isoform c and isoform d appear to have a minor role. Isoform b and isoform f are required for the organization of unc-15/paramyosin into sarcomere thick filaments in body wall muscles. By binding mel-26, a substrate adapter of t [...]
   
 
 0.490
cdh-4
Cadherin-4; Potential calcium-dependent cell-adhesion protein that controls axon guidance in the ventral cord.
      
 0.461
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.