STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F11C3.1ATP-dependent DNA helicase. (431 aa)    
Predicted Functional Partners:
pcn-1
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.525
div-1
DNA polymerase alpha subunit B; May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery. Required for the distribution of pie-1 in cell divsion.
   
 
 0.511
asfl-1
Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
   
 
 0.503
unc-85
Probable histone chaperone asf-1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
   
 
 0.503
Y54E5B.2
WD_REPEATS_REGION domain-containing protein.
   
    0.448
pezo-1
Piezo-type mechanosensitive ion channel component.
   
 
 0.437
nol-56
Nucleolar protein 56; Required for 60S ribosomal subunit synthesis. Belongs to the NOP5/NOP56 family.
   
    0.436
dna-2
Yeast DNA helicase/endonuclease family.
    
 
 0.426
orc-5
ORC (Origin Recognition Complex) subunit.
    
 
 0.413
Y23H5B.5
WD_REPEATS_REGION domain-containing protein.
   
    0.403
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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