STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
col-17COLlagen. (277 aa)    
Predicted Functional Partners:
sqt-1
Cuticle collagen sqt-1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. This is a collagen critical for organismal morphogenesis. Mutations in sqt-1 can lengthen, shorten, or helically twist the entire animal.
   
  
 0.944
dpy-13
Cuticle collagen dpy-13; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Mutations in dpy-13 affects the body shape.
   
  
 0.873
rol-8
Cuticle collagen 6; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment.
   
  
 0.868
col-90
Putative cuticle collagen 90; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (By similarity).
   
  
 0.863
math-28
MATH (Meprin-associated Traf homology) domain containing.
    
 
 0.764
T14B4.19
Uncharacterized protein.
      
 0.760
col-87
COLlagen.
      
 0.759
col-49
Col_cuticle_N domain-containing protein.
   
  
 0.731
sqt-2
Col_cuticle_N domain-containing protein.
   
  
 0.723
col-73
Col_cuticle_N domain-containing protein.
   
  
 0.722
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.