STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
col-73Col_cuticle_N domain-containing protein. (285 aa)    
Predicted Functional Partners:
F11G11.13
Phosphagen kinase C-terminal domain-containing protein; Belongs to the ATP:guanido phosphotransferase family.
      
 0.919
T01C8.3
Uncharacterized protein.
      
 0.917
dpy-13
Cuticle collagen dpy-13; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Mutations in dpy-13 affects the body shape.
  
   
0.859
dpy-4
Col_cuticle_N domain-containing protein.
  
   
0.858
F11G11.15
Uncharacterized protein.
      
 0.819
E01G4.6
Uncharacterized protein.
   
  
 0.731
R11G11.6
DUF148 domain-containing protein.
   
  
 0.731
Y47D7A.13
Uncharacterized protein.
   
  
 0.731
col-17
COLlagen.
   
  
 0.722
gst-8
Probable glutathione S-transferase 8; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Sigma family.
      
 0.698
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.