STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mpst-4Thiosulfate/3-mercaptopyruvate sulfurtransferase. (323 aa)    
Predicted Functional Partners:
suox-1
Cytochrome b5 heme-binding domain-containing protein.
    
 0.969
moc-3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
   
 0.954
B0205.6
Aminotran_5 domain-containing protein.
   
 0.953
cth-1
CystaTHionine gamma lyase.
  
 
 0.948
cth-2
Putative cystathionine gamma-lyase 2; Belongs to the trans-sulfuration enzymes family.
  
 
 0.948
got-2.2
Aspartate aminotransferase.
  
 
 0.943
got-2.1
Aspartate aminotransferase.
  
 
 0.943
got-1.2
Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the central nervous system.
  
 
 0.943
mpst-1
Putative thiosulfate sulfurtransferase mpst-1.
  
  
 
0.915
ethe-1
Lactamase_B domain-containing protein.
  
 
 0.913
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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