STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nep-5NEPrilysin metallopeptidase family. (655 aa)    
Predicted Functional Partners:
nep-9
NEPrilysin metallopeptidase family.
   
  
 0.979
nep-8
Peptidase_M13 domain-containing protein.
   
  
 0.970
nep-7
NEPrilysin metallopeptidase family.
   
  
 0.967
nep-16
Peptidase_M13_N domain-containing protein.
      
 0.805
nep-6
NEPrilysin metallopeptidase family.
   
  
0.720
nep-19
NEPrilysin metallopeptidase family.
   
  
0.555
F47B3.1
Tyrosine-protein phosphatase.
   
   0.542
kin-26
Tyrosine-protein kinase.
   
   0.539
kin-5
Tyrosine-protein kinase.
   
   0.539
kin-21
Tyrosine-protein kinase.
   
   0.539
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.