node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F13B12.1 | T24H10.1 | F13B12.1.1 | T24H10.1.1 | IWS1-like protein. | Putative transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity). Belongs to the TFS-II family. | 0.949 |
F13B12.1 | Y54G11A.11 | F13B12.1.1 | Y54G11A.11.2 | IWS1-like protein. | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. | 0.908 |
F13B12.1 | ZK973.1 | F13B12.1.1 | ZK973.1.1 | IWS1-like protein. | S1 motif domain-containing protein. | 0.929 |
F13B12.1 | ama-1 | F13B12.1.1 | F36A4.7.2 | IWS1-like protein. | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] | 0.941 |
F13B12.1 | ctr-9 | F13B12.1.1 | B0464.2a.1 | IWS1-like protein. | RNA polymerase-associated protein CTR9; Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification (By similarity). Ctr-9 is required for epidermal microtubule organization during morphogenesis. | 0.921 |
F13B12.1 | emb-5 | F13B12.1.1 | T04A8.14.1 | IWS1-like protein. | Suppressor of Ty 6 homolog; May regulate transcriptional elongation by RNA polymerase II. Required for several aspects of morphogenesis of C.elegans, including regulation of division in the germline and gut and specification of ventral-uterine precursor cell fate; Belongs to the SPT6 family. | 0.998 |
F13B12.1 | rpb-3 | F13B12.1.1 | C36B1.3.1 | IWS1-like protein. | RPOLD domain-containing protein. | 0.973 |
F13B12.1 | spt-16 | F13B12.1.1 | F55A3.3.1 | IWS1-like protein. | FACT complex subunit spt-16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment [...] | 0.959 |
F13B12.1 | spt-4 | F13B12.1.1 | F54C4.2.1 | IWS1-like protein. | Transcription elongation factor SPT4; May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex. | 0.918 |
F13B12.1 | spt-5 | F13B12.1.1 | K08E4.1.2 | IWS1-like protein. | Transcription elongation factor SPT5; May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex. Belongs to the SPT5 family. | 0.972 |
T24H10.1 | F13B12.1 | T24H10.1.1 | F13B12.1.1 | Putative transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity). Belongs to the TFS-II family. | IWS1-like protein. | 0.949 |
T24H10.1 | Y54G11A.11 | T24H10.1.1 | Y54G11A.11.2 | Putative transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity). Belongs to the TFS-II family. | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. | 0.420 |
T24H10.1 | ZK973.1 | T24H10.1.1 | ZK973.1.1 | Putative transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity). Belongs to the TFS-II family. | S1 motif domain-containing protein. | 0.486 |
T24H10.1 | ama-1 | T24H10.1.1 | F36A4.7.2 | Putative transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity). Belongs to the TFS-II family. | DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] | 0.998 |
T24H10.1 | ctr-9 | T24H10.1.1 | B0464.2a.1 | Putative transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity). Belongs to the TFS-II family. | RNA polymerase-associated protein CTR9; Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification (By similarity). Ctr-9 is required for epidermal microtubule organization during morphogenesis. | 0.827 |
T24H10.1 | emb-5 | T24H10.1.1 | T04A8.14.1 | Putative transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity). Belongs to the TFS-II family. | Suppressor of Ty 6 homolog; May regulate transcriptional elongation by RNA polymerase II. Required for several aspects of morphogenesis of C.elegans, including regulation of division in the germline and gut and specification of ventral-uterine precursor cell fate; Belongs to the SPT6 family. | 0.973 |
T24H10.1 | rpb-3 | T24H10.1.1 | C36B1.3.1 | Putative transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity). Belongs to the TFS-II family. | RPOLD domain-containing protein. | 0.991 |
T24H10.1 | spt-16 | T24H10.1.1 | F55A3.3.1 | Putative transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity). Belongs to the TFS-II family. | FACT complex subunit spt-16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment [...] | 0.905 |
T24H10.1 | spt-4 | T24H10.1.1 | F54C4.2.1 | Putative transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity). Belongs to the TFS-II family. | Transcription elongation factor SPT4; May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex. | 0.993 |
T24H10.1 | spt-5 | T24H10.1.1 | K08E4.1.2 | Putative transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity). Belongs to the TFS-II family. | Transcription elongation factor SPT5; May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex. Belongs to the SPT5 family. | 0.997 |