STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F13B12.3Uncharacterized protein. (717 aa)    
Predicted Functional Partners:
gtl-1
LSDAT_euk domain-containing protein.
   
 
 
0.433
trpl-2
TRP-channel-Like.
   
 
 
0.412
gtl-2
Gon-Two Like (TRP subfamily).
   
 
 
0.406
trp-1
Transient-receptor-potential-like protein; Could mediate calcium entry and form a calcium permeant channel; Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily.
   
 
  0.406
osm-9
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
     
  0.400
spe-41
TRP homologous cation channel protein.
     
  0.400
trp-2
TRP (Transient receptor potential) channel family; Belongs to the transient receptor (TC 1.A.4) family.
     
 
0.400
cup-5
PKD_channel domain-containing protein.
     
  0.400
gon-2
Transient receptor potential channel; Required for initiation and continuation of postembryonic mitotic cell divisions of gonadal cells Z1 and Z4. Zygotic expression is necessary for hermaphrodite fertility. May be a cation channel. Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily.
     
 
0.400
ced-11
Protein ced-11; Plays a major role in programmed cell death.
     
  0.400
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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