node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alp-1 | cpna-1 | T11B7.4d.1 | F31D5.3b.1 | ALP/Enigma encoding. | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | 0.453 |
alp-1 | lim-8 | T11B7.4d.1 | F28F5.3c.1 | ALP/Enigma encoding. | LIM domain family. | 0.846 |
alp-1 | lim-9 | T11B7.4d.1 | F25H5.1i.1 | ALP/Enigma encoding. | LIM domain family. | 0.538 |
alp-1 | scpl-1 | T11B7.4d.1 | B0379.4b.1 | ALP/Enigma encoding. | CTD small phosphatase-like protein 1; Phosphatase which may play a role in the egg laying muscles. | 0.625 |
alp-1 | unc-15 | T11B7.4d.1 | F07A5.7a.2 | ALP/Enigma encoding. | Paramyosin; Structural component of the muscle thick filaments which is involved in assembly and organization of sarcomere myofilaments. Involved in ovulation. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord. Belongs to the paramyosin family. | 0.505 |
alp-1 | unc-89 | T11B7.4d.1 | C09D1.1b.1 | ALP/Enigma encoding. | Muscle M-line assembly protein unc-89; Structural component of the muscle M line which is involved in assembly and organization of sarcomere myofilaments. The large isoform a, isoform b, isoform d and isoform f play an essential role in maintaining the organization of sarcomeres but not myofilament alignment during body wall muscle development whereas the small isoform c and isoform d appear to have a minor role. Isoform b and isoform f are required for the organization of unc-15/paramyosin into sarcomere thick filaments in body wall muscles. By binding mel-26, a substrate adapter of t [...] | 0.861 |
alp-1 | unc-95 | T11B7.4d.1 | Y105E8A.6.1 | ALP/Enigma encoding. | LIM domain-containing protein unc-95; Required for the assembly and integrity of muscle dense bodies, which establish the adhesion sites of the muscle cells to the extracellular matrix. Decreased localization of unc-95 to dense bodies and their subsequent dissociation plays an important role in ecdysis during molting. Involved in the organization of the muscle sarcomeric structure and thereby required for locomotion. | 0.760 |
alp-1 | unc-96 | T11B7.4d.1 | F13C5.6b.1 | ALP/Enigma encoding. | Uncharacterized protein. | 0.838 |
alp-1 | unc-98 | T11B7.4d.1 | F08C6.7.1 | ALP/Enigma encoding. | Zinc finger protein unc-98; Probable transcription factor required for muscle structure. Its dual subcellular localization suggests that it may function both as a muscle adhesion complex protein and as a transcription factor, or work together with transcription factors, to influence gene expression. Thought to act as a molecular bridge between unc-97 and myo-3 at the M-line of muscles, possibly in a signaling role. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord. | 0.823 |
cpna-1 | alp-1 | F31D5.3b.1 | T11B7.4d.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | ALP/Enigma encoding. | 0.453 |
cpna-1 | lim-8 | F31D5.3b.1 | F28F5.3c.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | LIM domain family. | 0.404 |
cpna-1 | lim-9 | F31D5.3b.1 | F25H5.1i.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | LIM domain family. | 0.892 |
cpna-1 | scpl-1 | F31D5.3b.1 | B0379.4b.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | CTD small phosphatase-like protein 1; Phosphatase which may play a role in the egg laying muscles. | 0.883 |
cpna-1 | unc-15 | F31D5.3b.1 | F07A5.7a.2 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | Paramyosin; Structural component of the muscle thick filaments which is involved in assembly and organization of sarcomere myofilaments. Involved in ovulation. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord. Belongs to the paramyosin family. | 0.467 |
cpna-1 | unc-89 | F31D5.3b.1 | C09D1.1b.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | Muscle M-line assembly protein unc-89; Structural component of the muscle M line which is involved in assembly and organization of sarcomere myofilaments. The large isoform a, isoform b, isoform d and isoform f play an essential role in maintaining the organization of sarcomeres but not myofilament alignment during body wall muscle development whereas the small isoform c and isoform d appear to have a minor role. Isoform b and isoform f are required for the organization of unc-15/paramyosin into sarcomere thick filaments in body wall muscles. By binding mel-26, a substrate adapter of t [...] | 0.687 |
cpna-1 | unc-95 | F31D5.3b.1 | Y105E8A.6.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | LIM domain-containing protein unc-95; Required for the assembly and integrity of muscle dense bodies, which establish the adhesion sites of the muscle cells to the extracellular matrix. Decreased localization of unc-95 to dense bodies and their subsequent dissociation plays an important role in ecdysis during molting. Involved in the organization of the muscle sarcomeric structure and thereby required for locomotion. | 0.505 |
cpna-1 | unc-96 | F31D5.3b.1 | F13C5.6b.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | Uncharacterized protein. | 0.837 |
cpna-1 | unc-97 | F31D5.3b.1 | F14D12.2.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | LIM domain-containing protein unc-97; Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Probably function in adherens junction. Affects the structural integrity of the integrin containing muscle adherens junctions and contributes to the mechanosensory functions of touch neurons. | 0.703 |
cpna-1 | unc-98 | F31D5.3b.1 | F08C6.7.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | Zinc finger protein unc-98; Probable transcription factor required for muscle structure. Its dual subcellular localization suggests that it may function both as a muscle adhesion complex protein and as a transcription factor, or work together with transcription factors, to influence gene expression. Thought to act as a molecular bridge between unc-97 and myo-3 at the M-line of muscles, possibly in a signaling role. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord. | 0.555 |
lim-8 | alp-1 | F28F5.3c.1 | T11B7.4d.1 | LIM domain family. | ALP/Enigma encoding. | 0.846 |