STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F13H10.3Sodium-coupled neutral amino acid transporter 9 homolog; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. (617 aa)    
Predicted Functional Partners:
lmtr-2
Ragulator complex protein LAMTOR2 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. May activate the TOR signaling cascade in response to amino acids; Belongs to the GAMAD family.
    
 0.997
lmtr-3
Late endosomal/lysosomal adaptor, Mapk (MAPK) and mToR (MTOR) activator homolog.
   
 0.996
raga-1
RAs-related GTP-binding protein A.
   
 0.946
ragc-1
RAs-related GTP binding protein C homolog.
   
 0.938
slc-36.2
Aa_trans domain-containing protein.
    
 
 0.928
skat-1
Probable amino acid transporter skat-1; Plays a role in the accumulation of vital dyes and endogenous fluorescent compounds in lysosome related organelles. Has an effect on lysosome related organelle (LRO) function, in a pathway with serotonin.
   
 
 0.921
lmtr-5
Late endosomal/lysosomal adaptor, Mapk (MAPK) and mToR (MTOR) activator homolog.
   
 
  0.901
T04C4.1
Uncharacterized protein.
   
 
 0.865
flcn-1
UDENN FLCN/SMCR8-type domain-containing protein.
    
 
 0.795
vha-16
V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.
    
 0.768
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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