STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
upb-1CN hydrolase domain-containing protein. (387 aa)    
Predicted Functional Partners:
dpyd-1
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). Involved in the degradation of the chemotherapeutic drug 5-fluorouracil.
  
 
 0.986
dhp-2
Dihydropyrimidinase 2; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
 
 
 0.975
dhp-1
Dihydropyrimidinase 1.
 
 
 0.975
gta-1
Probable 4-aminobutyrate aminotransferase, mitochondrial.
  
 
 0.964
T09B4.8
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.951
alh-9
Putative aldehyde dehydrogenase family 7 member A1 homolog; Belongs to the aldehyde dehydrogenase family.
   
 0.944
alh-12
Aldedh domain-containing protein.
   
 0.941
alh-1
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
   
 0.927
alh-5
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.925
alh-11
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
   
 0.924
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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