STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F13H8.9Aminotran_5 domain-containing protein. (387 aa)    
Predicted Functional Partners:
Y45F10D.4
NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
  
 0.994
seld-1
Probable selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. Belongs to the selenophosphate synthase 1 family. Class I subfamily.
   
 0.976
frh-1
Frataxin, mitochondrial; Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization. Belongs to the frataxin family.
   
 0.960
lpd-8
Nfu_N domain-containing protein.
  
 0.934
trxr-1
Thioredoxin reductase 1; Together with glutathione reductase gsr-1, required for the reduction of disulfide groups in the cuticle during molting.
  
 0.917
trxr-2
Probable glutathione reductase 2; Maintains high levels of reduced glutathione in the cytosol.
  
 0.917
mocs-1
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
    
 0.855
F53G2.12
Uncharacterized protein; Belongs to the complex I LYR family.
   
 
 0.853
Y39B6A.3
Fe-S_biosyn domain-containing protein.
  
 
 0.810
dnj-15
J domain-containing protein.
  
 
 0.766
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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