node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F14F9.3 | ZK177.8 | F14F9.3.1 | ZK177.8a.1 | Uncharacterized protein. | Uncharacterized protein ZK177.8. | 0.892 |
F14F9.3 | sid-5 | F14F9.3.1 | F14B8.2.1 | Uncharacterized protein. | Systemic RNA interference defective protein 5; Plays a role in RNA-mediated gene silencing by mediating transport of both ingested and endogenous dsRNA between cells. Not required for the uptake of dsRNA from the intestinal lumen. | 0.692 |
ZK177.8 | F14F9.3 | ZK177.8a.1 | F14F9.3.1 | Uncharacterized protein ZK177.8. | Uncharacterized protein. | 0.892 |
ZK177.8 | sid-5 | ZK177.8a.1 | F14B8.2.1 | Uncharacterized protein ZK177.8. | Systemic RNA interference defective protein 5; Plays a role in RNA-mediated gene silencing by mediating transport of both ingested and endogenous dsRNA between cells. Not required for the uptake of dsRNA from the intestinal lumen. | 0.670 |
chc-1 | rab-7 | T20G5.1.1 | W03C9.3.2 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | RAB family. | 0.535 |
chc-1 | rsd-3 | T20G5.1.1 | C34E11.1.1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | ENTH domain-containing protein. | 0.827 |
chc-1 | sid-3 | T20G5.1.1 | B0302.1a.1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | Tyrosine-protein kinase sid-3; Tyrosine-protein kinase which plays a role in RNA-mediated gene silencing by mediating import of double-stranded RNA (dsRNA) into cells. Not required for import of ingested dsRNA into intestinal cells but involved in subsequent export from intestinal cells to internal tissues. | 0.719 |
chc-1 | sid-5 | T20G5.1.1 | F14B8.2.1 | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | Systemic RNA interference defective protein 5; Plays a role in RNA-mediated gene silencing by mediating transport of both ingested and endogenous dsRNA between cells. Not required for the uptake of dsRNA from the intestinal lumen. | 0.459 |
chup-1 | rsd-3 | ZK721.1a.1 | C34E11.1.1 | CHolesterol UPtake associated. | ENTH domain-containing protein. | 0.660 |
chup-1 | sid-1 | ZK721.1a.1 | C04F5.1.2 | CHolesterol UPtake associated. | Systemic RNA interference defective protein 1; Plays a role in RNA-mediated gene silencing by acting cell- autonomously as a channel for the transport of double-stranded RNA (dsRNA) between cells. Mediates the spread of dsRNA and subsequent silencing of genes in cells distant from the site of dsRNA introduction. Selective for dsRNA. Preferentially binds long dsRNA, from 50 base pairs up to 700. Short 20 base-pair long molecules are not bound. May also bind dsDNA, but with lower affinity. Binding may be sequence-independent. Belongs to the SID1 family. | 0.431 |
chup-1 | sid-2 | ZK721.1a.1 | ZK520.2.1 | CHolesterol UPtake associated. | Systemic RNA interference defective protein 2; Plays a role in RNA-mediated gene silencing by mediating endocytic uptake of double-stranded RNA (dsRNA) ingested from the environment into intestinal cells from the intestinal lumen. Selective for dsRNAs of at least 50 bp. | 0.663 |
chup-1 | sid-5 | ZK721.1a.1 | F14B8.2.1 | CHolesterol UPtake associated. | Systemic RNA interference defective protein 5; Plays a role in RNA-mediated gene silencing by mediating transport of both ingested and endogenous dsRNA between cells. Not required for the uptake of dsRNA from the intestinal lumen. | 0.465 |
rab-7 | chc-1 | W03C9.3.2 | T20G5.1.1 | RAB family. | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | 0.535 |
rab-7 | sec-22 | W03C9.3.2 | F55A4.1.1 | RAB family. | Yeast SEC homolog; Belongs to the synaptobrevin family. | 0.540 |
rab-7 | sid-5 | W03C9.3.2 | F14B8.2.1 | RAB family. | Systemic RNA interference defective protein 5; Plays a role in RNA-mediated gene silencing by mediating transport of both ingested and endogenous dsRNA between cells. Not required for the uptake of dsRNA from the intestinal lumen. | 0.459 |
rsd-3 | chc-1 | C34E11.1.1 | T20G5.1.1 | ENTH domain-containing protein. | Probable clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis ; Belongs to the clathrin heavy chain family. | 0.827 |
rsd-3 | chup-1 | C34E11.1.1 | ZK721.1a.1 | ENTH domain-containing protein. | CHolesterol UPtake associated. | 0.660 |
rsd-3 | sec-22 | C34E11.1.1 | F55A4.1.1 | ENTH domain-containing protein. | Yeast SEC homolog; Belongs to the synaptobrevin family. | 0.463 |
rsd-3 | sid-1 | C34E11.1.1 | C04F5.1.2 | ENTH domain-containing protein. | Systemic RNA interference defective protein 1; Plays a role in RNA-mediated gene silencing by acting cell- autonomously as a channel for the transport of double-stranded RNA (dsRNA) between cells. Mediates the spread of dsRNA and subsequent silencing of genes in cells distant from the site of dsRNA introduction. Selective for dsRNA. Preferentially binds long dsRNA, from 50 base pairs up to 700. Short 20 base-pair long molecules are not bound. May also bind dsDNA, but with lower affinity. Binding may be sequence-independent. Belongs to the SID1 family. | 0.818 |
rsd-3 | sid-2 | C34E11.1.1 | ZK520.2.1 | ENTH domain-containing protein. | Systemic RNA interference defective protein 2; Plays a role in RNA-mediated gene silencing by mediating endocytic uptake of double-stranded RNA (dsRNA) ingested from the environment into intestinal cells from the intestinal lumen. Selective for dsRNAs of at least 50 bp. | 0.851 |