STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acp-2ACid Phosphatase family; Belongs to the histidine acid phosphatase family. (408 aa)    
Predicted Functional Partners:
F57A10.2
Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
      
 0.911
T24F1.4
Uncharacterized protein.
      
 0.808
gad-2
Uncharacterized protein.
      
 0.700
sdz-19
SKN-1 Dependent Zygotic transcript.
      
 0.700
Y71H10B.1
Uncharacterized protein.
      
 0.697
gad-3
Probable aldehyde oxidase gad-3; May be involved in the metabolism of 1-methylnicotinamide (MNA). Linked to regulation of longevity through generation of reactive oxygen species, where it probably functions in a pathway downstream of the sirtuin sir-2.1 and the nicotinamide N-methyltransferase anmt-1. Belongs to the xanthine dehydrogenase family.
   
  
 0.635
tbx-11
Putative T-box protein 11.
   
  
 0.538
ugt-23
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.505
str-46
Seven TM Receptor.
      
 0.463
T10E9.2
Uncharacterized protein.
      
 0.463
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.