node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C47G2.3 | tin-10 | C47G2.3.1 | Y66D12A.22.1 | Mitochondrial import inner membrane translocase subunit tim-22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). | Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (Probable). | 0.974 |
C47G2.3 | tin-9.1 | C47G2.3.1 | C06G3.11.1 | Mitochondrial import inner membrane translocase subunit tim-22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). | Mitochondrial import inner membrane translocase subunit Tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (Probable). Belongs to the small Tim family. | 0.979 |
C47G2.3 | vab-3 | C47G2.3.1 | F14F3.1a.1 | Mitochondrial import inner membrane translocase subunit tim-22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). | Homeobox domain-containing protein. | 0.907 |
ceh-32 | egl-5 | W05E10.3.1 | C08C3.1b.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | Homeobox protein egl-5; Essential for the determination of specific neurons. | 0.400 |
ceh-32 | eya-1 | W05E10.3.1 | C49A1.4a.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | 0.934 |
ceh-32 | lin-32 | W05E10.3.1 | T14F9.5.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | Protein lin-32; Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs. Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis. | 0.538 |
ceh-32 | vab-3 | W05E10.3.1 | F14F3.1a.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | Homeobox domain-containing protein. | 0.902 |
egl-5 | ceh-32 | C08C3.1b.1 | W05E10.3.1 | Homeobox protein egl-5; Essential for the determination of specific neurons. | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | 0.400 |
egl-5 | lin-32 | C08C3.1b.1 | T14F9.5.1 | Homeobox protein egl-5; Essential for the determination of specific neurons. | Protein lin-32; Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs. Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis. | 0.725 |
egl-5 | vab-3 | C08C3.1b.1 | F14F3.1a.1 | Homeobox protein egl-5; Essential for the determination of specific neurons. | Homeobox domain-containing protein. | 0.719 |
eya-1 | ceh-32 | C49A1.4a.1 | W05E10.3.1 | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | 0.934 |
eya-1 | lin-32 | C49A1.4a.1 | T14F9.5.1 | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | Protein lin-32; Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs. Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis. | 0.489 |
eya-1 | mab-21 | C49A1.4a.1 | F35G12.6.1 | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | Protein male abnormal 21; Acts in a cell autonomous fashion to specify the properties of the sensory ray and non-autonomously in the choice of hypodermal versus neuroblast cell fate. Belongs to the mab-21 family. | 0.507 |
eya-1 | vab-3 | C49A1.4a.1 | F14F3.1a.1 | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | Homeobox domain-containing protein. | 0.876 |
hlh-17 | lin-32 | F38C2.2.1 | T14F9.5.1 | BHLH domain-containing protein. | Protein lin-32; Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs. Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis. | 0.531 |
hlh-17 | vab-3 | F38C2.2.1 | F14F3.1a.1 | BHLH domain-containing protein. | Homeobox domain-containing protein. | 0.708 |
ina-1 | vab-3 | F54G8.3.1 | F14F3.1a.1 | Integrin alpha ina-1; Plays a role in cell migration, axon fasciculation, and morphogenesis. During gonad morphogenesis, involved in distal tip cells (DTC)-mediated guidance of gonad elongation, in maintaining their sharp tapering morphology and in their migration. Involved in the anterior-posterior positioning of QR neuroblast descendants by regulating the migratory speed of QR.p. Probably by acting as a receptor for apoptotic cells, plays a role in the clearance of apoptotic cells during mid-embryogenesis. Belongs to the integrin alpha chain family. | Homeobox domain-containing protein. | 0.724 |
lin-32 | ceh-32 | T14F9.5.1 | W05E10.3.1 | Protein lin-32; Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs. Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis. | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | 0.538 |
lin-32 | egl-5 | T14F9.5.1 | C08C3.1b.1 | Protein lin-32; Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs. Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis. | Homeobox protein egl-5; Essential for the determination of specific neurons. | 0.725 |
lin-32 | eya-1 | T14F9.5.1 | C49A1.4a.1 | Protein lin-32; Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs. Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis. | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | 0.489 |