STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F14H12.3Uncharacterized protein. (257 aa)    
Predicted Functional Partners:
ran-2
Ran GTPase-activating protein 2; GTPase system comprising ran-1, ran-2 and ran-3 is essential in nucleocytoplasmic trafficking. Ran-2 is a GTPase activator for the nuclear RAS-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state. Required for correct chromosome alignment and segregation on the metaphase plate.
   
 
 0.925
xpo-1
Importin N-terminal domain-containing protein.
   
 
 0.918
imb-1
Importin N-terminal domain-containing protein.
   
 
 0.913
xpo-3
Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.
   
 
 0.907
ran-4
Probable nuclear transport factor 2; Facilitates protein transport into the nucleus. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity).
   
 
 0.885
imb-2
Importin N-terminal domain-containing protein.
   
 
 0.883
xpo-2
Importin N-terminal domain-containing protein.
   
 
 0.876
T16G12.6
Xpo1 domain-containing protein.
    
 
 0.861
npp-11
Nuclear Pore complex Protein.
   
 
 0.794
npp-9
Nuclear Pore complex Protein.
   
 
 0.785
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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