STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhr-176Nuclear Hormone Receptor family. (345 aa)    
Predicted Functional Partners:
cyp-35D1
CYtochrome P450 family; Belongs to the cytochrome P450 family.
   
 
 0.932
cyp-34A7
CYtochrome P450 family; Belongs to the cytochrome P450 family.
    
 
 0.804
cyp-35B3
CYtochrome P450 family; Belongs to the cytochrome P450 family.
    
 
 0.749
ugt-25
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.666
cyp-13A1
Putative cytochrome P450 CYP13A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
    
 
 0.632
ugt-37
UDP-GlucuronosylTransferase.
      
 0.615
ben-1
Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
      
 0.612
F19F10.1
ETS domain-containing protein.
  
 
   0.546
ets-7
ETS domain-containing protein.
  
 
   0.545
ugt-13
UDP-GlucuronosylTransferase.
   
  
 0.544
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.