STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
obr-2Oxysterol-binding protein; Belongs to the OSBP family. (436 aa)    
Predicted Functional Partners:
hpo-28
Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
    
 
 0.802
hhat-2
Homolog of Hedgehog AcylTransferase; Belongs to the membrane-bound acyltransferase family.
      
 0.802
math-46
MATH (Meprin-associated Traf homology) domain containing.
      
 0.801
acp-5
ACid Phosphatase family; Belongs to the histidine acid phosphatase family.
      
 0.758
T19D2.2
Putative prenylated protein tyrosine phosphatase.
      
 0.700
Y57A10A.14
Uncharacterized protein.
      
 0.700
skat-1
Probable amino acid transporter skat-1; Plays a role in the accumulation of vital dyes and endogenous fluorescent compounds in lysosome related organelles. Has an effect on lysosome related organelle (LRO) function, in a pathway with serotonin.
      
 0.697
cuc-1
HMA domain-containing protein.
      
 0.693
taf-6.1
TAF domain-containing protein.
      
 0.668
apm-3
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.