STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pals-1Protein containing ALS2cr12 (ALS2CR12) signature. (296 aa)    
Predicted Functional Partners:
pals-40
Protein containing ALS2cr12 (ALS2CR12) signature.
      
 0.850
pals-22
Protein containing ALS2cr12 (ALS2CR12) signature.
   
  
 0.667
pamn-1
Probable peptidyl-glycine alpha-amidating monooxygenase pamn-1; Probable bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity; In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
      
 0.587
M01G12.7
Uncharacterized protein.
   
  
 0.477
C37H5.14
RAI1 domain-containing protein.
      
 0.463
pgal-1
Probable peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity (By similarity).
      
 0.463
M01G12.14
Uncharacterized protein.
      
 0.463
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.