node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
E02H1.5 | Y55F3BR.1 | E02H1.5.1 | Y55F3BR.1.1 | Uncharacterized protein E02H1.5. | Uncharacterized protein. | 0.890 |
E02H1.5 | arch-1 | E02H1.5.1 | C43H8.1.1 | Uncharacterized protein E02H1.5. | Protein archease-like; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB (F16A11.2). | 0.629 |
E02H1.5 | rtcb-1 | E02H1.5.1 | F16A11.2a.1 | Uncharacterized protein E02H1.5. | RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs. Required for the ligation of mRNAs and specifically, regulates xbp-1 mRNA splicing during the endoplasmic reticulum stress- induced unfolded protein response. Has a neuroprotective role in the age-dependent degeneration of dopamine neurons, which is mediated by xbp-1. Belongs to the RtcB family. | 0.949 |
E02H1.5 | tofu-2 | E02H1.5.1 | F20A1.9.1 | Uncharacterized protein E02H1.5. | B30.2/SPRY domain-containing protein. | 0.893 |
R02F2.9 | Y55F3BR.1 | R02F2.9.1 | Y55F3BR.1.1 | RF_PROK_I domain-containing protein. | Uncharacterized protein. | 0.420 |
R02F2.9 | rtcb-1 | R02F2.9.1 | F16A11.2a.1 | RF_PROK_I domain-containing protein. | RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs. Required for the ligation of mRNAs and specifically, regulates xbp-1 mRNA splicing during the endoplasmic reticulum stress- induced unfolded protein response. Has a neuroprotective role in the age-dependent degeneration of dopamine neurons, which is mediated by xbp-1. Belongs to the RtcB family. | 0.761 |
R02F2.9 | tofu-2 | R02F2.9.1 | F20A1.9.1 | RF_PROK_I domain-containing protein. | B30.2/SPRY domain-containing protein. | 0.422 |
Y55F3BR.1 | E02H1.5 | Y55F3BR.1.1 | E02H1.5.1 | Uncharacterized protein. | Uncharacterized protein E02H1.5. | 0.890 |
Y55F3BR.1 | R02F2.9 | Y55F3BR.1.1 | R02F2.9.1 | Uncharacterized protein. | RF_PROK_I domain-containing protein. | 0.420 |
Y55F3BR.1 | eif-2alpha | Y55F3BR.1.1 | Y37E3.10a.1 | Uncharacterized protein. | S1 motif domain-containing protein. | 0.402 |
Y55F3BR.1 | rtcb-1 | Y55F3BR.1.1 | F16A11.2a.1 | Uncharacterized protein. | RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs. Required for the ligation of mRNAs and specifically, regulates xbp-1 mRNA splicing during the endoplasmic reticulum stress- induced unfolded protein response. Has a neuroprotective role in the age-dependent degeneration of dopamine neurons, which is mediated by xbp-1. Belongs to the RtcB family. | 0.874 |
ZK1127.5 | arch-1 | ZK1127.5.1 | C43H8.1.1 | Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. | Protein archease-like; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB (F16A11.2). | 0.417 |
ZK1127.5 | cutl-14 | ZK1127.5.1 | B0511.5.1 | Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. | ZP domain-containing protein. | 0.400 |
ZK1127.5 | rtcb-1 | ZK1127.5.1 | F16A11.2a.1 | Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. | RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs. Required for the ligation of mRNAs and specifically, regulates xbp-1 mRNA splicing during the endoplasmic reticulum stress- induced unfolded protein response. Has a neuroprotective role in the age-dependent degeneration of dopamine neurons, which is mediated by xbp-1. Belongs to the RtcB family. | 0.950 |
arch-1 | E02H1.5 | C43H8.1.1 | E02H1.5.1 | Protein archease-like; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB (F16A11.2). | Uncharacterized protein E02H1.5. | 0.629 |
arch-1 | ZK1127.5 | C43H8.1.1 | ZK1127.5.1 | Protein archease-like; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB (F16A11.2). | Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. | 0.417 |
arch-1 | rtcb-1 | C43H8.1.1 | F16A11.2a.1 | Protein archease-like; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB (F16A11.2). | RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs. Required for the ligation of mRNAs and specifically, regulates xbp-1 mRNA splicing during the endoplasmic reticulum stress- induced unfolded protein response. Has a neuroprotective role in the age-dependent degeneration of dopamine neurons, which is mediated by xbp-1. Belongs to the RtcB family. | 0.937 |
cutl-14 | ZK1127.5 | B0511.5.1 | ZK1127.5.1 | ZP domain-containing protein. | Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. | 0.400 |
cutl-14 | rtcb-1 | B0511.5.1 | F16A11.2a.1 | ZP domain-containing protein. | RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs. Required for the ligation of mRNAs and specifically, regulates xbp-1 mRNA splicing during the endoplasmic reticulum stress- induced unfolded protein response. Has a neuroprotective role in the age-dependent degeneration of dopamine neurons, which is mediated by xbp-1. Belongs to the RtcB family. | 0.800 |
eif-2alpha | Y55F3BR.1 | Y37E3.10a.1 | Y55F3BR.1.1 | S1 motif domain-containing protein. | Uncharacterized protein. | 0.402 |