STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F16F9.4Uncharacterized protein. (396 aa)    
Predicted Functional Partners:
R02F2.8
Aa_trans domain-containing protein.
   
  
 0.902
C05D12.1
Uncharacterized protein.
   
  
 0.898
M176.5
Uncharacterized protein.
   
  
 0.892
twk-36
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.850
best-3
Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family.
   
  
 0.816
aqp-8
AQuaPorin or aquaglyceroporin related; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
 0.715
F16F9.1
LITAF domain-containing protein.
   
  
 0.674
exl-1
Chloride intracellular channel exl-1; Probable chloride channel; Belongs to the chloride channel CLIC family.
      
 0.670
twk-23
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.669
daf-41
Co-chaperone protein daf-41; Co-chaperone for hsp90/daf-21. Involved in regulation of longevity, larval entry and exit from the dauer stage of development and response to environmental cues, such as oxidative stress, in a temperature-dependent manner. Role in daf-16 and hsf-1 inhibition at elevated temperatures. Belongs to the p23/wos2 family.
      
 0.663
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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