node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hgrs-1 | stam-1 | C07G1.5.2 | C34G6.7a.1 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. | 0.999 |
hgrs-1 | tsg-101 | C07G1.5.2 | C09G12.9.1 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. | Tumor Susceptibility Gene homolog. | 0.998 |
hgrs-1 | vps-2 | C07G1.5.2 | Y46G5A.12.1 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. | Related to yeast Vacuolar Protein Sorting factor. | 0.955 |
hgrs-1 | vps-20 | C07G1.5.2 | Y65B4A.3.1 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. | Related to yeast Vacuolar Protein Sorting factor. | 0.951 |
hgrs-1 | vps-22 | C07G1.5.2 | C27F2.5.1 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. | 0.936 |
hgrs-1 | vps-24 | C07G1.5.2 | T27F7.1.2 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. | Related to yeast Vacuolar Protein Sorting factor. | 0.938 |
hgrs-1 | vps-25 | C07G1.5.2 | W02A11.2.2 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. | Related to yeast Vacuolar Protein Sorting factor. | 0.940 |
hgrs-1 | vps-28 | C07G1.5.2 | Y87G2A.10a.1 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex, a regulator of vesicular trafficking process; Belongs to the VPS28 family. | 0.979 |
hgrs-1 | vps-36 | C07G1.5.2 | F17C11.8.2 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. | GLUE N-terminal domain-containing protein. | 0.954 |
hgrs-1 | vps-37 | C07G1.5.2 | CD4.4.1 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. | VPS37 C-terminal domain-containing protein. | 0.937 |
stam-1 | hgrs-1 | C34G6.7a.1 | C07G1.5.2 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. | 0.999 |
stam-1 | tsg-101 | C34G6.7a.1 | C09G12.9.1 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. | Tumor Susceptibility Gene homolog. | 0.991 |
stam-1 | vps-2 | C34G6.7a.1 | Y46G5A.12.1 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. | Related to yeast Vacuolar Protein Sorting factor. | 0.871 |
stam-1 | vps-20 | C34G6.7a.1 | Y65B4A.3.1 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. | Related to yeast Vacuolar Protein Sorting factor. | 0.924 |
stam-1 | vps-22 | C34G6.7a.1 | C27F2.5.1 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. | 0.881 |
stam-1 | vps-24 | C34G6.7a.1 | T27F7.1.2 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. | Related to yeast Vacuolar Protein Sorting factor. | 0.927 |
stam-1 | vps-25 | C34G6.7a.1 | W02A11.2.2 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. | Related to yeast Vacuolar Protein Sorting factor. | 0.914 |
stam-1 | vps-28 | C34G6.7a.1 | Y87G2A.10a.1 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex, a regulator of vesicular trafficking process; Belongs to the VPS28 family. | 0.959 |
stam-1 | vps-36 | C34G6.7a.1 | F17C11.8.2 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. | GLUE N-terminal domain-containing protein. | 0.933 |
stam-1 | vps-37 | C34G6.7a.1 | CD4.4.1 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. | VPS37 C-terminal domain-containing protein. | 0.895 |