STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
his-34Histone H2B 1. (122 aa)    
Predicted Functional Partners:
his-33
Histone H2A.
 
 
 
 0.937
his-35
Histone H2A; Belongs to the histone H2A family.
 
 
 
 0.923
emb-5
Suppressor of Ty 6 homolog; May regulate transcriptional elongation by RNA polymerase II. Required for several aspects of morphogenesis of C.elegans, including regulation of division in the germline and gut and specification of ventral-uterine precursor cell fate; Belongs to the SPT6 family.
   
 
 0.861
nsun-4
SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.850
his-31
Histone H4.
 
 
 
 0.841
tric-1B.2
Trimeric intracellular cation channel type 1B.2; Potassium channel that mediates transmembrane potassium transport (By similarity). Might be required for maintenance of rapid intracellular calcium release (By similarity). May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity). Binds phosphatidylinositol 4,5-bisphosphate (PIP2).
      
 0.818
his-30
Histone H2A.
 
 
 
 0.796
his-43
Histone H2A.
 
 
 
 0.791
his-65
Histone H2A.
 
 
 
 0.768
his-64
Histone H4.
 
 
 
 0.745
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.