STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nlp-7Neuropeptide-like protein 7; May regulate lifespan in response to food availability and oxidative stress. (121 aa)    
Predicted Functional Partners:
cup-4
Acetylcholine receptor-like protein cup-4; Thought to regulate endocytosis in coelomocytes through modulation of phospholipase C activity. Possible acetylcholine receptor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
   
  
 0.806
nlp-5
Neuropeptide-Like Protein.
   
  
 0.764
nlp-9
Neuropeptide-Like Protein.
   
  
 0.760
nlp-10
Neuropeptide-Like Protein.
   
  
 0.756
nlp-3
Neuropeptide-Like Protein.
   
  
 0.727
nlp-15
Neuropeptide-Like Protein.
   
 
 0.723
flp-11
FMRFamide-like neuropeptides 11; FMRFamides and FMRFamide-like peptides are neuropeptides. [ASGGMRNALVRF-amide]: Acts as a ligand for the npr-22 receptor in vitro; Belongs to the FARP (FMRFamide related peptide) family.
   
  
 0.705
EGAP5.1
Uncharacterized protein.
   
  
 0.692
nlp-57
Neuropeptide-Like Protein.
   
  
 0.692
nlp-73
Neuropeptide-Like Protein.
   
  
 0.692
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (28%) [HD]