STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srx-977TM_GPCR_Srx domain-containing protein. (317 aa)    
Predicted Functional Partners:
F19B10.10
Uncharacterized protein.
      
 0.892
F40H7.12
Uncharacterized protein.
      
 0.808
srh-217
Serpentine Receptor, class H.
      
 0.668
W09C3.8
Uncharacterized protein.
   
  
 0.662
F54E12.2
Uncharacterized protein.
      
 0.660
psf-1
Probable DNA replication complex GINS protein PSF1; The GINS complex plays an essential role in the initiation of DNA replication.
      
 0.660
gpc-1
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.619
fbxb-59
FBA_2 domain-containing protein.
      
 0.585
dcar-1
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.535
osm-10
Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
      
 0.533
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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