node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C17H11.2 | C49F5.3 | C17H11.2.1 | C49F5.3.1 | Uncharacterized protein. | Uncharacterized protein. | 0.875 |
C17H11.2 | pzf-1 | C17H11.2.1 | T05G11.1a.1 | Uncharacterized protein. | Paired Zinc Finger protein. | 0.906 |
C17H11.2 | sea-1 | C17H11.2.1 | F19B10.9.1 | Uncharacterized protein. | T-box transcription factor 18; Probable transcriptional regulator involved in developmental processes. Activates xol-1 transcription, either directly or indirectly, establishing that xol-1 acts as the master regulator to integrate both X chromosome and autosomal signals to determine sexual fate. | 0.713 |
C49F5.3 | C17H11.2 | C49F5.3.1 | C17H11.2.1 | Uncharacterized protein. | Uncharacterized protein. | 0.875 |
C49F5.3 | pzf-1 | C49F5.3.1 | T05G11.1a.1 | Uncharacterized protein. | Paired Zinc Finger protein. | 0.899 |
C49F5.3 | sea-1 | C49F5.3.1 | F19B10.9.1 | Uncharacterized protein. | T-box transcription factor 18; Probable transcriptional regulator involved in developmental processes. Activates xol-1 transcription, either directly or indirectly, establishing that xol-1 acts as the master regulator to integrate both X chromosome and autosomal signals to determine sexual fate. | 0.758 |
asd-1 | ceh-39 | R74.5a.2 | T26C11.7.2 | RRM domain-containing protein. | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | 0.891 |
asd-1 | sea-1 | R74.5a.2 | F19B10.9.1 | RRM domain-containing protein. | T-box transcription factor 18; Probable transcriptional regulator involved in developmental processes. Activates xol-1 transcription, either directly or indirectly, establishing that xol-1 acts as the master regulator to integrate both X chromosome and autosomal signals to determine sexual fate. | 0.861 |
asd-1 | sea-2 | R74.5a.2 | K10G6.3g.1 | RRM domain-containing protein. | C2H2-type domain-containing protein. | 0.855 |
asd-1 | sex-1 | R74.5a.2 | F44A6.2.2 | RRM domain-containing protein. | Steroid hormone receptor family member cnr14; Belongs to the nuclear hormone receptor family. NR1 subfamily. | 0.832 |
asd-1 | xol-1 | R74.5a.2 | C18A11.5c.1 | RRM domain-containing protein. | XO lethal protein 1; Acts as a primary sex-determining factor that promotes sexual differentiation. Absolutely required for proper sexual differentiation and male viability. High expression during gastrulation triggers male development, while low expression at that time triggers hermaphrodite development. Although related to GHMP kinase, its mode of action remains unclear; Belongs to the GHMP kinase family. Xol-1 subfamily. | 0.810 |
ceh-39 | asd-1 | T26C11.7.2 | R74.5a.2 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | RRM domain-containing protein. | 0.891 |
ceh-39 | fox-1 | T26C11.7.2 | T07D1.4d.1 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | Sex determination protein fox-1; A member of the sex determination pathway involved in making the distinction between one and two X-chromosomes. RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUG-3' elements. Regulates alternative splicing of tissue-specific exons. Promotes binding of sup-12 to target RNA. | 0.814 |
ceh-39 | sea-1 | T26C11.7.2 | F19B10.9.1 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | T-box transcription factor 18; Probable transcriptional regulator involved in developmental processes. Activates xol-1 transcription, either directly or indirectly, establishing that xol-1 acts as the master regulator to integrate both X chromosome and autosomal signals to determine sexual fate. | 0.893 |
ceh-39 | sea-2 | T26C11.7.2 | K10G6.3g.1 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | C2H2-type domain-containing protein. | 0.851 |
ceh-39 | sex-1 | T26C11.7.2 | F44A6.2.2 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | Steroid hormone receptor family member cnr14; Belongs to the nuclear hormone receptor family. NR1 subfamily. | 0.852 |
ceh-39 | xol-1 | T26C11.7.2 | C18A11.5c.1 | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | XO lethal protein 1; Acts as a primary sex-determining factor that promotes sexual differentiation. Absolutely required for proper sexual differentiation and male viability. High expression during gastrulation triggers male development, while low expression at that time triggers hermaphrodite development. Although related to GHMP kinase, its mode of action remains unclear; Belongs to the GHMP kinase family. Xol-1 subfamily. | 0.857 |
fox-1 | ceh-39 | T07D1.4d.1 | T26C11.7.2 | Sex determination protein fox-1; A member of the sex determination pathway involved in making the distinction between one and two X-chromosomes. RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUG-3' elements. Regulates alternative splicing of tissue-specific exons. Promotes binding of sup-12 to target RNA. | Homeobox protein ceh-39; Probable DNA-binding regulatory protein involved in cell-fate specification; Belongs to the CUT homeobox family. | 0.814 |
fox-1 | sea-1 | T07D1.4d.1 | F19B10.9.1 | Sex determination protein fox-1; A member of the sex determination pathway involved in making the distinction between one and two X-chromosomes. RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUG-3' elements. Regulates alternative splicing of tissue-specific exons. Promotes binding of sup-12 to target RNA. | T-box transcription factor 18; Probable transcriptional regulator involved in developmental processes. Activates xol-1 transcription, either directly or indirectly, establishing that xol-1 acts as the master regulator to integrate both X chromosome and autosomal signals to determine sexual fate. | 0.811 |
fox-1 | sea-2 | T07D1.4d.1 | K10G6.3g.1 | Sex determination protein fox-1; A member of the sex determination pathway involved in making the distinction between one and two X-chromosomes. RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUG-3' elements. Regulates alternative splicing of tissue-specific exons. Promotes binding of sup-12 to target RNA. | C2H2-type domain-containing protein. | 0.832 |