STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mltn-10MLt-TeN (Mlt-10) related. (607 aa)    
Predicted Functional Partners:
snb-1
Synaptobrevin-1; Involved in the targeting and/or fusion of transport vesicles to their target membrane. Acts in neuronal exocytosis of synaptic transmission. Likely to have a role in cholinergic transmisson. Required for viability, coordinated movement and M3 pharynx motor neuron function.
    
 
 0.793
snap-1
SNAP (Soluble NSF Attachment Protein) homolog.
    
 
 0.791
snb-2
V-SNARE coiled-coil homology domain-containing protein.
    
 
 0.736
cuti-1
CUTicle and epithelial Integrity.
      
 0.660
unc-18
Putative acetylcholine regulator unc-18; May participate in the axonal transport system and influences the acetylcholine flow in motor neurons. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent state that precedes each larval molt ; Belongs to the STXBP/unc-18/SEC1 family.
   
 
 0.629
T07A9.10
Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.
   
 
 0.629
sri-18
Serpentine Receptor, class I.
   
 
 0.612
ric-4
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
   
 
 0.612
sec-22
Yeast SEC homolog; Belongs to the synaptobrevin family.
    
 
 0.605
ykt-6
YKT6 (Yeast v-SNARE) homolog; Belongs to the synaptobrevin family.
    
 
 0.601
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.