Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| egg-3 | iglr-1 | F44F4.2.2 | F20D1.7.1 | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | Ig-like domain-containing protein. | 0.400 |
| egg-3 | lron-6 | F44F4.2.2 | F37E3.2.1 | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | ELRR (Extracellular Leucine-Rich Repeat) ONly. | 0.400 |
| iglr-1 | egg-3 | F20D1.7.1 | F44F4.2.2 | Ig-like domain-containing protein. | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | 0.400 |
| iglr-1 | jnk-1 | F20D1.7.1 | B0478.1a.1 | Ig-like domain-containing protein. | Stress-activated protein kinase jnk-1; Serine/threonine-protein kinase which responds to activation by environmental stress by phosphorylating a number of transcription factors such as daf-16, and thus regulates transcriptional activity. By phosphorylating daf-16, plays a role in daf-16 nuclear translocation in intestinal cells in response to environmental stresses such as heat and oxidative stresses. Downstream of jkk-1, may coordinate locomotion via type-D GABAergic motoneurons and regulates synaptic vesicle transport in conjunction with unc-16. Independently of jkk-1, may regulate s [...] | 0.412 |
| iglr-1 | kynu-1 | F20D1.7.1 | C15H9.7.1 | Ig-like domain-containing protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.741 |
| iglr-1 | lat-1 | F20D1.7.1 | B0457.1a.1 | Ig-like domain-containing protein. | Latrophilin-like protein 1; Has a role in the establishment of anterior-posterior polarity in tissues during embryogenesis. Required for the alignment of the mitotic spindles and division planes. May have a role in cell death events. Required for normal defection and oocyte fertilization. Involved in sperm function. Operates in pharyngeal pumping during feeding. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | 0.715 |
| iglr-1 | lron-6 | F20D1.7.1 | F37E3.2.1 | Ig-like domain-containing protein. | ELRR (Extracellular Leucine-Rich Repeat) ONly. | 0.401 |
| iglr-1 | rcan-1 | F20D1.7.1 | F54E7.7.1 | Ig-like domain-containing protein. | Calcipressin-like protein; Inhibits tax-6/calcineurin A phosphatase activity and thereby negatively regulates calcineurin-mediated functions. Plays a role in modulating temperature-dependent calcium responses in AFD neurons and in addition, also negatively regulates thermotaxis in a tax-6-dependent manner in AFD neurons. In response to changes in intracellular calcium levels may also regulate nuclear translocation of transcriptional regulators such as crtc-1. May play a role in regulating body size. Plays a role in male tail tip morphogenesis. Belongs to the RCAN family. | 0.692 |
| iglr-1 | tag-322 | F20D1.7.1 | C33H5.10.1 | Ig-like domain-containing protein. | Uncharacterized protein. | 0.612 |
| iglr-1 | tsp-3 | F20D1.7.1 | Y39E4B.4.1 | Ig-like domain-containing protein. | TetraSPanin family; Belongs to the tetraspanin (TM4SF) family. | 0.758 |
| iglr-1 | tsp-7 | F20D1.7.1 | T23D8.2.1 | Ig-like domain-containing protein. | Tetraspanin. | 0.436 |
| jnk-1 | iglr-1 | B0478.1a.1 | F20D1.7.1 | Stress-activated protein kinase jnk-1; Serine/threonine-protein kinase which responds to activation by environmental stress by phosphorylating a number of transcription factors such as daf-16, and thus regulates transcriptional activity. By phosphorylating daf-16, plays a role in daf-16 nuclear translocation in intestinal cells in response to environmental stresses such as heat and oxidative stresses. Downstream of jkk-1, may coordinate locomotion via type-D GABAergic motoneurons and regulates synaptic vesicle transport in conjunction with unc-16. Independently of jkk-1, may regulate s [...] | Ig-like domain-containing protein. | 0.412 |
| kynu-1 | iglr-1 | C15H9.7.1 | F20D1.7.1 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | Ig-like domain-containing protein. | 0.741 |
| kynu-1 | tsp-3 | C15H9.7.1 | Y39E4B.4.1 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | TetraSPanin family; Belongs to the tetraspanin (TM4SF) family. | 0.581 |
| lat-1 | iglr-1 | B0457.1a.1 | F20D1.7.1 | Latrophilin-like protein 1; Has a role in the establishment of anterior-posterior polarity in tissues during embryogenesis. Required for the alignment of the mitotic spindles and division planes. May have a role in cell death events. Required for normal defection and oocyte fertilization. Involved in sperm function. Operates in pharyngeal pumping during feeding. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Ig-like domain-containing protein. | 0.715 |
| lat-1 | lron-6 | B0457.1a.1 | F37E3.2.1 | Latrophilin-like protein 1; Has a role in the establishment of anterior-posterior polarity in tissues during embryogenesis. Required for the alignment of the mitotic spindles and division planes. May have a role in cell death events. Required for normal defection and oocyte fertilization. Involved in sperm function. Operates in pharyngeal pumping during feeding. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | ELRR (Extracellular Leucine-Rich Repeat) ONly. | 0.715 |
| lron-6 | egg-3 | F37E3.2.1 | F44F4.2.2 | ELRR (Extracellular Leucine-Rich Repeat) ONly. | Protein tyrosine phosphatase-like protein egg-3; Probable pseudophosphatase required for the oocyte-to-zygote transition during which it regulates the polarized dispersal of the cortical actin cytoskeleton, the synthesis of the eggshell chitin layer and the formation of the polar bodies after meiosis I and II. Acts as scaffold to tether kinase mbk-2 and pseudophosphatases egg-4 and egg-5 to the oocyte cortex and thus restricts mbk-2 activity to the cortex during meiosis I. Regulates mbk-2 localization to cytoplasmic foci during meiosis II. Also required for chitin synthase chs-1 locali [...] | 0.400 |
| lron-6 | iglr-1 | F37E3.2.1 | F20D1.7.1 | ELRR (Extracellular Leucine-Rich Repeat) ONly. | Ig-like domain-containing protein. | 0.401 |
| lron-6 | lat-1 | F37E3.2.1 | B0457.1a.1 | ELRR (Extracellular Leucine-Rich Repeat) ONly. | Latrophilin-like protein 1; Has a role in the establishment of anterior-posterior polarity in tissues during embryogenesis. Required for the alignment of the mitotic spindles and division planes. May have a role in cell death events. Required for normal defection and oocyte fertilization. Involved in sperm function. Operates in pharyngeal pumping during feeding. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | 0.715 |
| rcan-1 | iglr-1 | F54E7.7.1 | F20D1.7.1 | Calcipressin-like protein; Inhibits tax-6/calcineurin A phosphatase activity and thereby negatively regulates calcineurin-mediated functions. Plays a role in modulating temperature-dependent calcium responses in AFD neurons and in addition, also negatively regulates thermotaxis in a tax-6-dependent manner in AFD neurons. In response to changes in intracellular calcium levels may also regulate nuclear translocation of transcriptional regulators such as crtc-1. May play a role in regulating body size. Plays a role in male tail tip morphogenesis. Belongs to the RCAN family. | Ig-like domain-containing protein. | 0.692 |
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