STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
csr-1Piwi domain-containing protein. (1030 aa)    
Predicted Functional Partners:
rde-4
RNA interference promoting factor.
   
 0.843
dcr-1
Death-promoting deoxyribonuclease; Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs. Seems to process the precursor of the small temporal RNA let-7 which is involved in developmental timing. Belongs to the helicase family. Dicer subfamily.
   
 0.817
ego-1
RNA-directed RNA polymerase related EGO-1.
   
  
 0.763
hmg-12
High mobility group protein I beta.
   
  
 0.726
taf-11.2
TAFII28 domain-containing protein.
   
 
 0.718
F45F2.10
ANK_REP_REGION domain-containing protein.
   
  
 0.712
F20D12.2
PCI domain-containing protein.
      
 0.698
ekl-1
Uncharacterized protein.
   
  
 0.696
R02F11.1
Uncharacterized protein.
    
 
 0.696
C47F8.7
Uncharacterized protein.
      
 0.692
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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