STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ceh-19Homeobox protein ceh-19. (199 aa)    
Predicted Functional Partners:
F20D12.2
PCI domain-containing protein.
      
 0.809
eat-17
Rab-GAP TBC domain-containing protein.
      
 0.667
lury-1
Luqin-like RYamide peptides lury-1; [LURY-1-1]: Acts as a ligand for the npr-22 receptor and controls food-related processes including feeding, lifespan, egg-laying and roaming behavior. Secreted in the presence of food, leading to reduced feeding and roaming behavior and increased egg laying and lifespan. Activity may be latent under normal conditions but induced under conditions that cause hyperactivation of the pharynx such as abrupt refeeding after starvation.
      
 0.660
hlh-15
BHLH domain-containing protein.
   
 
 0.600
tbx-8
T-box transcription factor tbx-8; Involved in the control of early morphogenesis of the intestine, hypodermis and body-wall muscle. Appears to have partially redundant function to tbx-9.
    
 
 0.495
tbx-9
T-box transcription factor tbx-9; Involved in the control of early morphogenesis of the intestine, hypodermis and body-wall muscle. Appears to have partially redundant function to tbx-8.
    
 
 0.486
lim-4
Putative transcription factor LIM-4.
   
 
 0.472
lim-7
LIM domain family.
   
 
 0.461
vha-15
Probable V-type proton ATPase subunit H 2; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity).
    
 
 0.457
lin-11
Protein lin-11; Probable transcription factor which is required for asymmetric division of vulval blast cells. Involved in olfactory plasticity probably by regulating the expression of transcription factor mbr-1 in RIF neurons. Plays a role in the chemorepulsive response toward ascaroside pheromones mediated by the ADL sensory neurons, probably by regulating E-box motif 5'-CANNTG-3' containing target genes in the ADL neurons. Plays a role in the differentiation of the ADL sensory neurons.
   
 
 0.451
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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