STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F20D6.11Rieske domain-containing protein. (549 aa)    
Predicted Functional Partners:
rad-50
DNA repair protein rad-50; Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis. In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity.
      
 0.831
nit-1
CN hydrolase domain-containing protein.
   
  
 0.819
gsr-1
Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol. Involved in resistance to oxidative stress and starvation. Together with thioredoxin reductase txtr- 1, required for the reduction of disulfide groups in the cuticle during molting.
  
 0.788
suox-1
Cytochrome b5 heme-binding domain-containing protein.
   
 0.784
ZK829.7
PKS_ER domain-containing protein.
  
  
 0.780
mrps-5
Putative 28S ribosomal protein S5, mitochondrial; Belongs to the universal ribosomal protein uS5 family.
   
 
 0.778
Y73F8A.27
2Fe-2S ferredoxin-type domain-containing protein.
  
 0.769
anat-1
AANAT (Arylalkylamine N-AcetylTransferase) homolog.
    
 
 0.765
moc-2
MoCF_biosynth domain-containing protein.
  
  
 0.708
ZK228.3
Acetyltransf_18 domain-containing protein.
      
 0.707
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.