node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
czw-1 | sec-20 | F20D12.4.2 | F40G9.1.1 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | Yeast SEC homolog; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | 0.803 |
czw-1 | smgl-1 | F20D12.4.2 | F20G4.1.1 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | Uncharacterized protein. | 0.999 |
czw-1 | syx-18 | F20D12.4.2 | T10H9.3.1 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | t-SNARE coiled-coil homology domain-containing protein. | 0.996 |
czw-1 | use-1 | F20D12.4.2 | Y110A7A.11.1 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | Vesicle transport protein USE1; SNARE that may be involved in targeting and fusion of Golgi- derived retrograde transport vesicles with the ER; Belongs to the USE1 family. | 0.969 |
sec-20 | czw-1 | F40G9.1.1 | F20D12.4.2 | Yeast SEC homolog; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores. Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex. The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores. To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC8 [...] | 0.803 |
sec-20 | smgl-1 | F40G9.1.1 | F20G4.1.1 | Yeast SEC homolog; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Uncharacterized protein. | 0.798 |
sec-20 | syx-18 | F40G9.1.1 | T10H9.3.1 | Yeast SEC homolog; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | t-SNARE coiled-coil homology domain-containing protein. | 0.979 |
sec-20 | use-1 | F40G9.1.1 | Y110A7A.11.1 | Yeast SEC homolog; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Vesicle transport protein USE1; SNARE that may be involved in targeting and fusion of Golgi- derived retrograde transport vesicles with the ER; Belongs to the USE1 family. | 0.998 |
smg-4 | smg-5 | F46B6.3b.1 | W02D3.8.1 | Smg4_UPF3 domain-containing protein. | Nonsense-mediated mRNA decay protein. | 0.995 |
smg-4 | smg-6 | F46B6.3b.1 | Y54F10AL.2a.1 | Smg4_UPF3 domain-containing protein. | PINc domain-containing protein. | 0.995 |
smg-4 | smg-8 | F46B6.3b.1 | K04B12.3a.1 | Smg4_UPF3 domain-containing protein. | Protein smg-8; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes. Belongs to the SMG8 family. | 0.889 |
smg-4 | smg-9 | F46B6.3b.1 | Y54E2A.2.1 | Smg4_UPF3 domain-containing protein. | Protein smg-9; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes. Belongs to the SMG9 family. | 0.879 |
smg-4 | smgl-1 | F46B6.3b.1 | F20G4.1.1 | Smg4_UPF3 domain-containing protein. | Uncharacterized protein. | 0.828 |
smg-4 | smgl-2 | F46B6.3b.1 | Y37E11AM.1a.1 | Smg4_UPF3 domain-containing protein. | Uncharacterized protein. | 0.862 |
smg-5 | smg-4 | W02D3.8.1 | F46B6.3b.1 | Nonsense-mediated mRNA decay protein. | Smg4_UPF3 domain-containing protein. | 0.995 |
smg-5 | smg-6 | W02D3.8.1 | Y54F10AL.2a.1 | Nonsense-mediated mRNA decay protein. | PINc domain-containing protein. | 0.994 |
smg-5 | smg-8 | W02D3.8.1 | K04B12.3a.1 | Nonsense-mediated mRNA decay protein. | Protein smg-8; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes. Belongs to the SMG8 family. | 0.984 |
smg-5 | smg-9 | W02D3.8.1 | Y54E2A.2.1 | Nonsense-mediated mRNA decay protein. | Protein smg-9; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes. Belongs to the SMG9 family. | 0.986 |
smg-5 | smgl-1 | W02D3.8.1 | F20G4.1.1 | Nonsense-mediated mRNA decay protein. | Uncharacterized protein. | 0.832 |
smg-5 | smgl-2 | W02D3.8.1 | Y37E11AM.1a.1 | Nonsense-mediated mRNA decay protein. | Uncharacterized protein. | 0.833 |